International Journal of Pharmaceutical Investigation, 2023, 13, 3, 641-645.
DOI: 10.5530/ijpi.13.3.079
Published: July 2023
Type: Original Article
Authors:
Kommanuru Venkata Ramakrishna Teja
Department of Pharmaceutical Sciences, Jawaharlal Nehru Technological Sciences-Anantapur, Ananthapuramu, Andhra Pradesh, INDIA.
Yiragamreddy Padmanabha Reddy
Department of Pharmaceutical Sciences, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, K. R. Palli Cross, Ananthapuramu-515721, (Affiliated to Jawaharlal Nehru Technological Sciences Anantapur), Ananthapuramu, Andhra Pradesh, INDIA.
Nayakanti Devanna
Department of Chemical Engineering, Jawaharlal Nehru Technological Sciences Anantapur, Ananthapuramu, Andhra Pradesh, INDIA.
ABSTRACT
Introduction: Although adverse drug reaction (ADR) monitoring is widely known, it is not practised in underdeveloped nations due to a lack of awareness and the absence of a central coordinating agency. The recent implementation of the National Pharmacovigilance Program has encouraged ADR monitoring in some centres. Aim: The purpose of this study was to evaluate the sternness of described ADRs, the additional financial cost associated with ADRs, and the present load of ADRs at the RDT hospital in Battalapalli, AP, India. Materials and Methods: Over 26 months of hospital admissions of patients, which were managed by hospital staff, a prospective, spontaneous reporting research was carried out. Results: 37 of the 74 adverse drug events (ADEs) that were reported by 56 individuals were indeed ADRs. There were 521 patients admitted, and 9.7% of those ADRs occurred during hospitalisation. Males (56%) had ADRs more often than females (44%). During the hospital stay, no discernible difference between males and females was seen. ADR rates were 19, 20, and 61% for paediatric, geriatric, and adult patients. There were 88 minor responses or 53.7% of the total. The majority of patients (72.6%) recovered from the incident. The majority of the responses show that they were unexpected and possibly avoidable. Conclusion: According to the study’s findings, 90% of ADRs might be prevented, saving the health system money and decreasing patient expenditures. To prevent unknown and severe ADRs, new medications should be continuously monitored.
Keywords: Adverse drug reaction, Awareness, Hospital, Patients, Pharmacovigilance.