International Journal of Pharmaceutical Investigation, 2023, 13, 3, 367-372.
DOI: 10.5530/ijpi.13.3.047
Published: July 2023
Type: Review Article
Authors:
Hindustan Abdul Ahad
Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, K.R. Palli Cross, Ananthapuramu, Andhra Pradesh, INDIA
Haranath Chinthaginjala
Department of Pharmaceutics, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, K.R. Palli Cross, Ananthapuramu, Andhra Pradesh, INDIA.
Bake Meharajunnisa
Department of Pharmaceutics, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, K.R. Palli Cross, Ananthapuramu, Andhra Pradesh, INDIA.
Nayakam Vandana
Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, K.R. Palli Cross, Ananthapuramu, Andhra Pradesh, INDIA
Renuka Gudisipalli
Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, K.R. Palli Cross, Ananthapuramu, Andhra Pradesh, INDIA
Peddapothula Nikhila
Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, K.R. Palli Cross, Ananthapuramu, Andhra Pradesh, INDIA
ABSTRACT
Matrix tablets are also referred to as sustained-release, controlled-release, or prolonged-release extended-release tablets, which will prolong the duration of the release of drug content into the systemic circulation. This work was to collect matter about polymers so far tried in making matrix tablets. Due to the prolonged duration of release, this may increase the bioavailability of the drug. They are made with various polymers, starting with cellulose, its derivatives, and plant gums or mucins. This data was obtained by viewing to peer-reviewed journals and magazines. These tablets can be prepared by direct compression of a blended mixture containing polymers, blending agents, glidants, and other additives. The blend was made as granules and compressed as tablets. The matrix tablets are sustained drug release forms and show better action. The study revealed that the matrix tablet is a simple method for extending drug release for a prolonged period.
Keywords: Drug, Gums, Literature, Matrix, Mucilage, Release.