International Journal of Pharmaceutical Investigation, 2022, 12, 2, 123-128.
DOI: 10.5530/ijpi.2022.2.23
Published: June 2022
Type: Review Article
Authors:
Sujata Sharma
School of Medical and Allied Sciences, K. R. Mangalam University, Sohna Road, Gurugram, INDIA.
Shweta Vashist
School of Medical and Allied Sciences, K. R. Mangalam University, Sohna Road, Gurugram, INDIA.
Avneet Kaur Lamba
Department of Pharmaceutical Sciences, Gurugram University, Gurugram, INDIA.
Saahil Arora
Department of Pharmaceutical Sciences, Gurugram University, Gurugram, INDIA.
Sucheta S
School of Medical and Allied Sciences, K. R. Mangalam University, Sohna Road, Gurugram, INDIA.
Abstract
Skin break out and eruptions is a typical incendiary issue among people of all age groups, but most common in adolescents. Skin break out development is reliant upon mechanisms, including follicular hyper keratinization, excess sebum secretion, colonization of pathogenic bacteria like Propionibacterium acnes and an incendiary course. Treatment strategies predominantly include the use of antibiotics. The use of antibiotics for the treatment of acne is associated with certain side effects like imbalance of skin and gut microbiome and multidrug resistance. This article explains the use of probiotics as a promising tool for the treatment of acne rather than antibiotics. Likewise talk about the favorable conditions and extra advantages offered by probiotics for stability enhancement of topical formulations. This review focuses on the use of bacteriocins in antiacne formulations, use of natural surfactant having additional antiacne properties and bacteriocins having anti-microbial and preservative action. Recent advancements in this field along with the patents are also enlisted
Keywords: Acne, Skin, Inflammation, Hyperproliferation, Psychological stress.