International Journal of Pharmaceutical Investigation, 2022, 12, 2, 117-122.
DOI: 10.5530/ijpi.2022.2.22
Published: June 2022
Type: Review Article
Authors:
Purushotham K N
Department of Pharmaceutical Chemistry, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, BG Nagara, Karnataka, INDIA.
TY Pasha
Department of Pharmaceutical Chemistry, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, BG Nagara, Karnataka, INDIA.
B Ramesh
Department of Pharmaceutical Chemistry, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, BG Nagara, Karnataka, INDIA.
DOI:
Abstract
Numerous bioactive heterocyclic products containing carbazole nucleus showed pharmacological and biological significance. Carbazole have been found in several of significant drug like fragments which provided a precious indication for action and in emerging new valuable derivatives. Carbazole possess several biological activities, i.e., action against viral infection, inflammation, cancer, HIV, microbial infection, tubercular infection, diabetes mellitus, malarial parasite infection, cholinesterase related disorders, etc. which made attention among research scholars to produce variety of carbazole molecules. This review revealed that carbazole molecules have different pharmacological actions and have a vast possible to be discovered for therapeutic potentials.
Keywords: Anticancer activities, Antimicrobial activities, Antifungal activities, Carbazole, Dibenzopyrrole, Tetrahydrocarbazole.