International Journal of Pharmaceutical Investigation, 2021, 11, 1, 118-122.
DOI: 10.5530/ijpi.2021.1.22
Published: April 2021
Type: Original Article
Authors:
Doa’a Anwar Ibrahim
Department of Clinical Pharmacy and Pharmacy Practice, Sana’a, YEMEN
Rawya Shehab
Department of Pharmacology, Faculty of Pharmacy, University of Science and Technology, Sana’a, YEMEN
Molok Saleh
Department of Pharmacology, Faculty of Pharmacy, University of Science and Technology, Sana’a, YEMEN
Shyma’a Ali
Department of Pharmacology, Faculty of Pharmacy, University of Science and Technology, Sana’a, YEMEN
Kawther Al-Hamati
Department of Pharmacology, Faculty of Pharmacy, University of Science and Technology, Sana’a, YEMEN
Abdulsalam Halboup
Department of Clinical Pharmacy and Pharmacy Practice, Sana’a, YEMEN
ABSTRACT
Background: The optimal intake of nutrients is a new approach to deriving nutrient requirements. Omega-3 is one of these nutrients that has a crucial role in body health. It can modulate inflammation, hyperlipidemia, platelet aggregation, and hypertension. Objectives: This study was designed as a pilot study to evaluate the efficacy and safety of omega-3 fatty acid in improving the level of Vitamin D and calcium among Childbearing age women that suffer from Vitamin D deficiency. Methods: 10 childbearing women with Vitamin D deficiency. They were selected randomly. The participants were allowed to take one capsule (1000mg) of omega 3 FA twice daily for 12 weeks. Results: Omega-3 FA showed significant beneficial effects on Vitamin D, calcium levels in Vitamin D deficit childbearing women. Additionally, it showed cardioprotective effects as it reduced bad lipids like cholesterol, LDL-c, risk factor and had worthwhile effects on blood coagulation. Conclusion: The outcomes of the present study suggest that omega-3 FA if taken regularly by childbearing women may improve their maternal outcomes and save their own lives and their babies. It may have a golden standard role in bone health through strength and activation of Vitamin D thus facilitates calcium absorption and increase bone mineral density. Additionally, it has cardioprotective and immune modulation effects.
Keywords: Omega-3 FA, Childbearing women, Vitamin D deficiency, Sana’ City, Yemen