International Journal of Pharmaceutical Investigation, 2021, 11, 1, 5-9
DOI: 10.5530/ijpi.2021.1.2
Published: December 2021
Type: Review Article
Authors:
Pradeep Kumar Yadalam
Department of Periodontics, SRM Kattankulatur Dental College and Hospital, Chennai, Tamil Nadu, INDIA.
Deepavalli Arumuganainar
Department of Periodontics, Ragas Dental College and Hospital, Chennai, Tamil Nadu, INDIA.
Rajapandian Kasipandian
Department of Periodontics, SRM Kattankulatur Dental College and Hospital, Chennai, Tamil Nadu, INDIA.
Kalaivani Varatharajan
Department of Periodontics, SRM Kattankulatur Dental College and Hospital, Chennai, Tamil Nadu, INDIA.
ABSTRACT
Nanotechnology is of intense interest to researchers due to the basic fact that the properties of the material can be effectively manipulated when the size is transformed to nanoscopic. New opportunities arise out of the unique features which have been effectually utilized in the development of nano pharmaceuticals. This has revolutionized the health care system extensively by its diverse applications in modern medicine and dental science. Material science and periodontics have jointly adopted this technology to produce nanoparticles for targeted drug delivery, which find considerable significance in the management of periodontal diseases. Periodontitis is principally polymicrobial in nature, affecting the supporting structures of the tooth. In addition to the conventional mechanical debridement, adjunctive chemical therapy is, at most times, required to resolve the chronic inflammation. Hence, targeted drug delivery using nanoparticles with improved pharmacological and therapeutic properties may form better treatment strategies for managing this chronic inflammation. As nanoscale technology finds a scope in varied applications in periodontics, this current review highlights the various nanoscale drug delivery systems for managing periodontal diseases.
Keywords:
Dendrimers, Liposomes, Nanocarriers, Nanofibers, Nanogels, Periodontal disease