International Journal of Pharmaceutical Investigation, 2022, 12, 2, 136-140.
DOI: 10.5530/ijpi.2022.2.25
Published: June 2022
Type: Review Article
Authors:
Payel Mukherjee
Department of Pharmaceutics, M.R. College of Pharmaceutical Sciences and Research, Bira, Balisha, North 24 Parganas, West Bengal, INDIA.
Arindam Chakraborty
Department of Pharmaceutical Biotechnology, School of Pharmacy, Seacom Skills University, Bolpur, Birbhum, West Bengal, INDIA.
Manas Chakraborty
Department of Pharmaceutical Biotechnology, Calcutta Institute of Pharmaceutical Technology and AHS, Banitabla, Uluberia, Howrah, West Bengal, INDIA.
Goutam Mukhopadhyay
Department of Pharmaceutics, BCDA College of Pharmacy and Technology, Campus 2, Hridaypur, Kolkata, West Bengal, INDIA.
Abstract
These days, carbon dots (CDs) are the rising stars of nanomaterials. Carbon dots (CDs) are small carbon nanoparticles with the same type of surface passivation (less than 10 nm in size). Researchers found C-dots by accident while purifying single-walled carbon nanotubes (SWCNTs) manufactured using the arc-discharge process. Toxic metal-based quantum dots are being replaced with carbon dots (QDs). Carbon dots are currently being prepared from a variety of natural resources in order to obtain self-passivated products at a reasonable cost. Because of their superior photo physical characteristics, biocompatibility, and low toxicity, carbon dots have prospective applications in bio sensing, bio imaging, and drug administration. Different synthetic processes, precursors, salient properties, and applications were reviewed in this review, as well as some future prospects, obstacles, and possible solutions for future development. Because of their tunable optical characteristics and better biocompatibility, luminous carbon-based nanomaterials have sparked a lot of scientific interest. Different light emission properties of carbon are discussed in this review. Distinct synthesis procedures have resulted in different carbon dots (CDs). Summarized here. The optical properties of CDs that haven’t been synthesized yet surface doping and element doping can be used to further control it. CDs are being functionalized for an adjustable band gap. As a result of their luminescent with reduced cytotoxicity and tunable optical characteristics CDs have been thoroughly investigated in terms of their potential uses in biomedicine, such as analytical sensors, and instruments for bioimaging. Fluorescent carbon dots are a new type of nanomaterial from the carbon family. Green CDs, which have attracted a lot of attention from researchers because of their better water solubility, high biocompatibility, and eco-friendly nature when compared to chemically generated CDs, can be made from a variety of inexpensive and renewable resources. The presence of heteroatoms on the surface of green CDs in the form of amine, hydroxyl, carboxyl, or thiol functional groups, which can improve their physicochemical qualities, quantum yield, and likelihood of visible light absorption, eliminates the need for additional surface passivation.
Keywords: Carbon dots, Surface passivation, Quantum dots, Bio-sensing, Bio-imaging.