International Journal of Pharmaceutical Investigation, 2019, 9, 2, 36-42.
DOI: 10.5530/ijpi.2019.2.8
Published: August 2019
Type: Review Article
Authors:
Nihar Ranjan Kar
Centurion University of Technology and Management, IDCO Indrustrial Area, Pitamahal, Rayagada, Odisha, INDIA.
ABSTRACT
Radiopharmaceuticals are exclusive medicinal formulations including radioisotopes which are utilized in foremost clinical areas for study, diagnosis and/or therapy. They are radioactive agents employed in nuclear medical field to demonstrate high and exact localization radioactivity into target tissue. Recently, however, there has been a considerable development of this division of nuclear medicine with the preamble of a quantity of new radionuclides and radiopharmaceuticals for the treatment of cancer, neuroendocrine disorder and other diseases. The application of definite radiotracers called radiopharmaceuticals for imaging organ function and disease states is an exceptional potential of nuclear medicine. Distinct other imaging modalities, for example- Computed Tomography (CT), Magnetic Resonance Imaging (MRI) and Ultrasonography (US), nuclear medicine procedures are competent of drawing physiological function and metabolic activity and thus giving more precise information about the organ function and dysfunction. This review focuses the production and therapeutic applications of radiopharmaceuticals which hold functional radio atoms.
Keywords: Compounding of radiopharmaceuticals, Radionuclides, Radioactive decay, Radioactive emission diagnostic imaging, Nuclear medicine.